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This is the protocol for a Campbell systematic review. The objectives are as follows: What is the association between marital transitions and physical health among people older than 60? What is the association between marital transitions and mental health among people older than 60? What is the role of gender, age, and education on the association between marital transitions and health among people older than 60? What is the influence of geographical region, housing, neighborhood, and social support on the association between marital transitions and health status among people older than 60?
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INTRODUCTION: COVID-19 has a serious impact on people's physical health and mental health. The COVID-19 pandemic forced college and university students to take online classes, which may have bad impacts on students' learning. In addition, the students lost many job opportunities during the pandemic. Faced with employment and study pressure and worried about the epidemic, college and university students were prone to increased overall negative emotion, anxiety and depression. Therefore, this systematic review and meta-analysis will be conducted to explore the impact of the COVID-19 pandemic on the mental health and learning of college and university students. METHODS AND ANALYSIS: We will conduct electronic literature search of the PubMed, Embase, Cochrane Library, Web of Science and Chinese National Knowledge Infrastructure databases. Two researchers will independently screen the studies, extract data and assess the quality of the included studies. Any disagreement will be resolved by the third investigator. The Newcastle-Ottawa Scale and other tools will be used to assess the risk of bias, according to the study design of included studies. OR, risk ratio, mean difference and 95% CI will be considered as the effect size. Heterogeneity between studies will be assessed by subgroup and sensitivity analysis, and publication bias will be detected by funnel plots, Begg's test and Egger's test. ETHICS AND DISSEMINATION: This systematic review and meta-analysis involves no patient contact and no interaction with healthcare providers or systems. We will disseminate the findings of this study through the presentation at scientific conferences and publication in a peer-reviewed journal. PROSPERO REGISTRATION NUMBER: CRD42020201132.
Assuntos
COVID-19 , Pandemias , Humanos , Saúde Mental , Metanálise como Assunto , Projetos de Pesquisa , SARS-CoV-2 , Estudantes , Revisões Sistemáticas como Assunto , UniversidadesRESUMO
BACKGROUND: Atrial fibrillation (AF) is the most common clinical arrhythmia and a major cause of morbidity and mortality in clinical practice. This study aims to determine the ranolazine for prevention and treatment of atrial fibrillation. METHOD: This study adheres to the Preferred Reporting Items for Systematic Reviews and Meta-analysis for Protocols. Chinese electronic Database (CBM, Wanfang, and CNKI) and international electronic databases (PubMed, Embase, Cochrane Library, and Web of Science) will be searched for all relevant published articles. We will apply no language or the year of publication restrictions. Study selection, data collection, and assessment of study bias will be conducted independently by a pair of independent reviewers. The Cochrane risk of bias (ROB) tool will be used for the risk of bias assessment. The quality of evidence will be evaluated by Grading of Recommendations Assessment Development and Evaluation (GRADE) system. The statistical analysis of this meta-analysis will be calculated by Review manager version 5.3. RESULTS: The results of this study will be published in a peer-reviewed journal. CONCLUSION: This review will evaluate the value of ranolazine interventions for patients with AF, and provide meaningful conclusions or high-level evidence for clinical practice and further research. TRIAL REGISTRATION: This study protocol was registered in open Science framework (OSF), (Registration DOI: 10.17605/OSF.IO/T6W9Q).
